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Autoantikroppar vid diagnostik av systemiska autoimmuna

Validated in WB, IP and tested in Mouse, Rat, Human. Cited in 53 publication(s). 343 products Anti-HMGCR antibodies are offered by a number of suppliers. This target gene encodes the protein '3-hydroxy-3-methylglutaryl-CoA reductase' in HPA008338 Sigma-Aldrich. Anti-HMGCR antibody produced in rabbit. Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered Anti-HMGCR antibody produced in rabbit (Anti-3-hydroxy-3-methylglutaryl-CoA reductase, LDLCQ3); ~ 1.0mg/mL, affinity isolated antibody; Suitable for western Anti-HMGCR Polyclonal, Catalog # 13533-1-AP.

After the discovery of anti-HMGCR autoantibodies, several international groups identified and characterized more patients, expanding the phenotypic spect … Recently, auto-antibodies (AAbs) to the enzyme, 3-hydroxy-3-methylglutaryl-CoA reductase (HMGCR) was shown to be a MSA that was strongly associated with immune mediated necrotising myopathy (Arthritis Rheum. 2010 Sep;62(9):2757-66. doi: 10.1002/art.27572). Invitrogen Anti-HMGCR Polyclonal, Catalog # PA5-37367. Tested in Western Blot (WB), Immunocytochemistry (ICC) and Immunohistochemistry (Paraffin) (IHC (P)) applications.

Immunofluorescence analysis of A-549 cells using HMGCR antibody (STJ115278). Blue: DAPI for nuclear staining. Western blot analysis of extracts of various cell lines, using HMGCR antibody (STJ115278) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) at 1:10000 dilution.Lysates/proteins: 25ug per lane.Blocking buffer: 3% nonfat dry milk in TBST.

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Independently reviewed in 5 review(s). HPA008338 Sigma-Aldrich Anti-HMGCR antibody produced in rabbit Prestige Antibodies ® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution . Synonym: Anti-3-Hydroxy-3-methylglutaryl-CoA reductase Human Protein Atlas Number HPA008338 Human Protein Atlas - View RNA & protein expression data of this target View application images and datasheets for 163 anti HMGCR Antibody antibodies from 20 leading antibody suppliers, plus reviews and the top related antibodies Immunohistochemistry of paraffin-embedded human small intestine using HMGCR antibody (STJ24046) at dilution of 1:200 (40x lens). Western blot analysis of extracts of Rat brain, using HMGCR Rabbit pAb (STJ24046) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) at 1:10000 dilution.Lysates/proteins: 25ug per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL HMGCR antibody LS-C318764 is an HRP-conjugated rabbit polyclonal antibody to human HMGCR (HMG-CoA Reductase).

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Anti-HMGCR antibody detection. Anti-HMGCR antibodies were measured by two ELISA tests (one home-made, one commercial) and confirmed by presence of anti-HMGCR antibody and confirm the diagnosis of HMGCR IMNM.

Aug 4, 2017 Anti-HMGCR Antibody–Related Necrotizing. Autoimmune Myopathy Mimicking Muscular. Dystrophy.

HMGCR Abs (3-Hydroxy-3-Methylglutaryl-Coenzyme A Reductase) are associated with necrotizing myopathy that is commonly related to statin exposure. Recently, auto-antibodies (AAbs) to the enzyme, 3-hydroxy-3-methylglutaryl-CoA reductase (HMGCR) was shown to be a MSA that was strongly associated with immune mediated necrotising myopathy (Arthritis Rheum. 2010 Sep;62(9):2757-66. doi: 10.1002/art.27572).
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AUTOIMMUNE MYOPATHIES - Neuromuscular Disorders

Dystrophy. Céline Tard1,2. Vincent Tiffreau1,3. May 11, 2016 Recently, it has been recognised that in rare instances, statins can induce an immune‐mediated necrotising myositis with antibodies against 3‐ Custom recombinant monoclonal antibody generation by Bio-Rad using HuCAL ® technology could allow you to carry out research that was previously Sep 29, 2017 LGI1/CASPR2-antibody encephalitis is an autoimmune encephalitis in which antibodies target LGI1 (leucine-rich glioma inactivated 1) or The ImmPRESS Excel kits are a two-step peroxidase polymer based detection system that include an unconjugated amplifier antibody. This intermediate skin and lung fibrosis and autoimmunity via interleukin-6 signaling. Abstract OBJECTIVE: The presence of anti-DNA topoisomerase I (anti-topo I) antibody . Categories: Prostate & urology · Patient empowerment · Personalised medicine · Medicines · R&D · Biology · Control, survivorships & outcomes · Antibodies & Maples Scientific Publishers is an online publishing house, promoting scientific research via its open access journals and also provides language translation, av P Mohassel · 2019 · Citerat av 19 — Using a few clinico-pathologic criteria, followed by autoantibody testing, we screened our cohort of patients with clinically suspected LGMD and HMGCR Antibody (H-300) has been replaced by a more specific monoclonal antibody, HMGCR (C-1) that provides a stronger signal & more reproducible data.

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551 ANA screen, ENA screen.